Maleic anhydride is a colorless to white solid that forms orthorhombic crystals and decomposes in water. Wear safety goggles or eye protection in combination with breathing protection if powder. Since it biodegrades in sewage treatment plants and hydrolyzes, it's likely that it will degrade in soil. ... Maleic anhydride is transported also as hot liquid (70°C); contact of the skin should be avoided. Maleic anhydride TWA: 0.01 mg/m 3(Vacated) TWA: 0.25 ppm (Vacated) TWA: 1 mg/m3 TWA: 0.25 ppm TWA: 1 mg/m3 IDLH: 10 mg/m TWA: 0.25 ppm TWA: 1 mg/m3 TWA: 0.01 ppm Legend ACGIH - American Conference of Governmental Industrial Hygienists OSHA - Occupational Safety and … Maleic Anhydride 95 - 100% 108-31-6 Get medical attention immediately. Risk Statements: 36/37/38 R36/37/38:Irritating to eyes, respiratory system and skin. Safety Data Sheet 24 hour Emergency Response No. safety hazards of Maleic Acid to potentially exposed workers. Ingestion: If not breathing, give artificial respiration. FIRST AID MEASURES General advice Consult a physician. Product Safety Assessment: Maleic Anhydride Last Revised: August 2015 Page 2 of 3 Potential Human Health Effects Occupational Exposure Potential for occupational exposure to Maleic Anhydride exists during manufacture, at transloading, storage and staging areas, and during mixing and sampling operations in the manufacture of other products. : 108-31-6 Molecular Weight: 98.06 Chemical Formula: C4H2O3 Company: ADDTEK CHEMICAL SHANGHAI CO LTD TEL: +86 21 63352916 FAX: +86 21 51010033EXT8839 Acute (short-term) inhalation exposure of humans to maleic anhydride has been observed to cause irritation of the respiratory tract and eye irritation. Target Organs: Lungs, respiratory system, eyes, Causes severe eye and skin irritation with possible Inhalation: Corrosive. Causes redness and Washington, DC: Manufacturing Chemists Association, p. 1-13. May cause asthmatic attacks due to allergic sensitization of the CDC twenty four seven. Environmental: Maleic anhydride's fate in soil is unknown. Maleic anhydride in daily doses of 20, 40,100, 250 or 600 mg/kg body weight, fed for 90 days to groups of 15 rats of each sex, caused macroscopic changes in the kidneys: enlargement and pale yellow discoloration. MCA [1974]. Hazard classification & labelling Hazard classification and labelling. A poison by intravenous route. Immediate medical attention is required. Do NOT induce vomiting. Index -No. Harmful if swallowed. Immediate medical attention is required. none Water, Foam, Alcohol resistant foam, ABC-powder Water jet Nitrogen oxides (NOx), Carbon monoxide (CO), Carbon dioxide (CO2) In … Chemical name :maleic anhydride Substance/mixture : Occupational exposure limits, if available, are listed in Section 8. (5,8) The vapor pressure for maleic anhydride is 0.1 to 0.2 mm Hg at 25 °C. Box 219, Batavia, IL 60510 (800) 452-1261 Chemtrec Emergency Phone Number: (800) 424-9974 The ‘Hazard classification and labelling’ section shows the hazards of a substance based on the standardised system of statements and pictograms established under the CLP (Classification Labelling and Packaging) Regulation. Recrystallize the maleic anhydride from toluene. Saving Lives, Protecting People, The National Institute for Occupational Safety and Health (NIOSH), National Institute for Occupational Safety and Health, A – NIOSH Potential Occupational Carcinogens, E – OSHA Respirator Requirements for Selected Chemicals, G – 1989 Air Contaminants Update Project: Exposure Limits NOT in Effect, Type C & CE – Definitions for Type C and Type CE Respirators, U.S. Department of Health & Human Services. 1.3 Details of the supplier of the safety data sheet Company : Central Drug House (P) Ltd 7/28 Vardaan House New Delhi-10002 INDIA Appearance: white lumps. SAFETY DATA SHEET (in accordance with Regulation (EU) 2015/830) 108120-Maleic anhydride Version: 3 Revision date: 19/04/2016 Page 2 of 9 Print date: 19/04/2016 -Continued on next page.- P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. exposure may cause allergic respiratory reaction (asthma). May cause skin sensitization, an allergic Histological examination revealed nephrosis which increased in severity with the dose above 100 mg/kg. System RfD (mg/kg-day) Basis PoD Composite UF Confidence; Urinary: 1 x 10 -1: Renal lesions: NOAEL : 1.0 x 10 1 mg/kg-day Click here for information on selection of N, R, or P filters.Any appropriate escape-type, self-contained breathing apparatus, Important additional information about respirator selection, cis-Butenedioic anhydride, 2,5-Furanedione, Maleic acid anhydride, Toxilic anhydride. Safety Data Sheet (Maleic Anhydride) DATE PREPARED: 9/3/2015 Page 7 of 9 OSHA: No component of this product, present at levels greater than or equal to 0.1%, is identified as a carcinogen or potential carcinogen by OSHA. Prolonged or repeated skin contact may cause dermatitis. Since it biodegrades in sewage treatment plants and hydrolyzes, it's likely that it will degrade in soil. Maleic Anhydride Safety Data Sheet International Diol Company SAFETY DATA SHEET according to Regulation (EC) No. Maleic Anhydride Flinn Scientific, Inc. P.O. P342+P311 If experiencing respiratory symptoms: Call a POISON CENTER/doctor. Moisture sensitive. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. Common Name Maleic Anhydride Synonym(s) 2,5Furandione Formula C 4 H 2 O 3 CAS Number 108316 COMPONENT CAS NUMBER CONCENTRATION Maleic Anhydride 108316 ≤ Section 4. : 108-31-6 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratory chemicals, Manufacture of substances 1.3 Details of the supplier of the safety data sheet Dissolve the residue in a minimal amount of chloroform. Harmful if swallowed. CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. double vision, and "halo" vision. Chemical safety data sheet sd-88: properties and essential information for safe handling and use of maleic anhydride. First Aid Measures Description of Firstaid Measures General Advice: Consult a physician. Colorless needles, white lumps, or pellets with an irritating, choking odor. Environmental: Maleic anhydride's fate in soil is unknown. Product name : Maleic anhydride Product Number : 63200 Brand : Sigma-Aldrich Index-No. NCI [1974]. The anhydride of maleic acid has five atoms in its cyclic molecule, the unsaturated bond undergoes free radical polymerization in the presence of an initiator. Maleic anhydride, polymers Safety Profile. Product name : Maleic Anhydride CAS-No. Product identifier Identification number Name of the substance Maleic anhydride 607-096-00-9 (Index number) Registration number 01-2119472428-31 Synonyms MAN Issue date 07-March-2019 Version number 01 Revision date-Supersedes date-1.2. Up to 10 mg/m3: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode£(APF = 50) Any self-contained breathing apparatus with a full facepiece(APF = 50) Any supplied-air respirator with a full facepiece, Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus, Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister having an N100, R100, or P100 filter. 108 -31 -6 203 -571 -6 607 -096 -00 -9 - 4. Show this safety data sheet to the doctor in attendance.Move out of dangerous area. (2) Conversion Factors: EC -No. tract irritation and possible burns. ], inhalation, ingestion, skin and/or eye contact, irritation nose, upper respiratory system; conjunctivitis; photophobia (abnormal visual intolerance to light), double vision; bronchial asthma; dermatitis, Centers for Disease Control and Prevention. Move out of dangerous area. skin. reaction, which becomes evident upon re-exposure to this material. Consult a physician. [Note: Reacts slowly with water (hydrolyzes) to form maleic acid. Polynt Group produces a great variety of anhydrides, but the most important ones are: Phthalic Anhydrides, Maleic Anhydride, Trimellitic Anhydride respiratory tract. Maleic anhydride CAS -No. cis-Butenedioic anhydride, 2,5-Furanedione, Maleic acid anhydride, Toxilic anhydride Colorless needles, white lumps, or pellets with an irritating, choking odor. Safety Statements :26-36/37/39 Causes redness and pain. Interagency Collaborative Group on Environmental Carcinogens. 5. Danger! Causes chemical burns to the respiratory tract. Potential Health Effects : 108-31-6 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratorychemicals, Industrial & for professional use only. May cause blistering of the skin. Maleic anhydride is used in the formulation of resins. Since it biodegrades in sewage treatment plants and hydrolyzes, it's likely that it will degrade in soil. Anhydrides. OSHA Vacated PELs: Acetic anhydride: No OSHA Vacated PELs are listed for this chemical. 6. Chem., 1979, 179, C19], and is considered an excellent dieneophile for Diels-Alder reactions [Felthouse, Timothy R. et al. Symptoms and effects are not known to date. Causes gastrointestinal tract burns. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. National Cancer Institute, June 17, 1974. Chronic: Exposure to high fume concentrations cause photophobia, Skin: 1272/2008, Regulation (EC) No.1907/2006 Maleic Anhydride, rev 2 7/2012 Page 2 Basis for Classification This substance is classified based on Directive 1272/2008/EC and its amendments (CLP Regulation,GHS) MALEIC ANHYDRIDE (108-31-6) MALEIC ACID page 2 of 6 This Fact Sheet is a summary source of information of all ... (as Maleic Anhydride) exists, use a MSHA/NIOSH approved self-contained breathing apparatus with a full facepiece operated in a … Memorandum. Wash out mouth with water. Add 0.98 g (0.01 mole) of maleic anhydride to a solution of 1.67 g (0.01 mole) of veratrylamine in 10 mL of chloroform. May cause digestive tract Substance Any concentration shown as a range is to protect confidentiality or is due to batch variation. Maleic anhydride released into water will hydrolyze rapidly (half-life 0.37 min) to maleic acid. Inhalation of high concentrations may cause pulmonary edema. You will be subject to the destination website's privacy policy when you follow the link. Exposure to maleic anhydride may occur from accidental releases to the environment or in workplaces where it is produced or used. A combination of these processes should be important. irritation with nausea, vomiting, and diarrhea. pain. (2) Maleic anhydride has an acrid odor, with an odor threshold of 0.32 parts per million (ppm). : 607-096-00-9 CAS-No. If inhaled If breathed in, move person into fresh air. First-aid measures General Advice Show this safety data sheet to the doctor in attendance. Combustible Solid, but may be difficult to ignite. MATERIAL SAFETY DATA SHEET MALEIC ANHYDRIDE 1. Rinse mouth with water (only if the person is conscious). When heated to decomposition it emits acrid smoke and irritating vapors. May cause conjunctivitis. Remove victim to fresh Maleic acid 110-16-7 >95 4. +86-532-8027466 SECTION 1: PRODUCT AND COMPANY IDENTIFICATION ... Acrylic acid maleic anhydride copolymer, aka: 2-propenoic acid, polymer with 2,5, furandion e (cis-butenedioic anhydride) 52255-49-9 : ... Acrylic Acid Maleic … Show this safety data sheet to the doctor in attendance. Maleic anhydride undergoes a potentially explosive exothermic Diels-Alder reaction with 1-methylsilacyclopenta-2,4-diene at 150C [Barton, T. J., J. Organomet. Reproductive Toxicity: No data available Reproductive toxicity - Rat - Oral Causes respiratory Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in … Maleic anhydride has several uses, almost all of them related to the synthesis of other chemicals as fumaric and tartaric acids, certain agricultural chemicals (i.e., maleic hydrazide, malathion), lubricants, surface active agents, resins in different products, dye intermediates, pharmaceuticals, and more. SAFETY DATA SHEET SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Stir the mixture for 10 min. Eye: Strong oxidizers, water, alkalis, metals, caustics & amines above 150°F Evaporate the chloroform in a hood. Causes skin burns. Causes eye burns. May cause allergic skin and respiratory reaction. The odour warning when the exposure limit value is exceeded is insufficient. Pesticide properties for Maleic hydrazide, including approvals, environmental fate, eco-toxicity and human health issues Repeated "Maleic Anhydride, Maleic Acid, and Fumaric Acid." Product Identification Synonyms: cis-Butenedioic anhydride; 2,5-furandione; toxilic anhydride CAS No. burns. 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